CloneID: M5
Antigen Long Description: (His)6-tagged fragment of rat NgR1 (amino acids 278-473).
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Rabbit IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q86UN2
Specificity Statement: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).
Application Notes (Clone): The antibody binds specifically to residues 379-448 of NgR1, a member of the Nogo-66 receptor family which inhibits axonal growth and sporulating in the CNS.
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