CloneID: 12H2
Antigen Long Description: The original antibody was generated by immunizing female BALB/c mice with human α4β2 receptor protein purified in n-dodecyl-β-D-maltopyranoside (DDM).
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P17787
Specificity Statement: This antibody recognizes human α4β2 receptor protein. The AChR responds by an extensive change in conformation after binding acetylcholine, that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.
Application Notes (Clone): The binding characterization of this antibody to human α4β2 nicotinic receptor was done using ELISA.
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