Anti-NKp46 (NKP46-4)

Anti-NKp46 [NKP46-4], Recombinant, scFv fragment (His)

CloneID: NKP46-4

Heavy Chain modification: ScFv

Antigen Long Description: The original antibody was isolated using phage display technology after three rounds of panning against human NKp-46.

Buffer Composition: PBS only.

Uniprot Accession No.: O76036

Specificity Statement: The antibody is specific for human NKp46. The antibody cross-reacts with cynomolgus monkey and rhesus macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells.

Application Notes (Clone): The binding specificity of this antibody towards human, cynomolgus monkey and rhesus monkey NKp-46 was determined using ELISA and flow cytometry. The binding of this antibody to NKp-46 expressed on the surface of CHOK1 and NK cells was confirmed using flow cytometry. The original IgG antibody bound ectodomain of human NKp-46 with a binding affinity of Kd= 1.1 nM. This binding of this antibody to NK cells resulted in an increase in the interferon gamma release (CN113637074).

• Artikelnummer: ABAAb03381-30.11-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03381-30.11-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Human, Primate, Cynomolgus Monkey (Primate)
• Klonalität: Recombinant
• Methode: ELISA, Flow Cytometry
• Isotyp: scFv fragment (His)