Anti-NS1 (clone n.10)

Anti-NS1 [clone n.10], Recombinant, IgG1 kappa, Human
Artikelnummer
ABAAb03635-10.3
Verpackungseinheit
100 μg
Hersteller
Absolute Antibody

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CloneID: clone n.10

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was originated from a phage display library by panning against the NS1 protein.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This full-length reformatted human antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q2F4N6

Specificity Statement: The antibody is specific for the E domain of the non-structural protein-1. The antibody reacts with viruses belonging to different subtypes and types including avian H5N1, swine H1N1 and H3N2, human H1N1 and H3N2 and influenza B virus. Non-structural protein-1 (NS1) is a multifunctional and conserved protein of influenza viruses. It is produced at the initial phase of the infection for suppressing and evading the host immune responses and enhancing the viral replication.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody detected the E domain of NS1 by western blot analysis. The original format of the antibody inhibited influenza virus replication in the infected MDCK cells. The clone could enter the influenza virus infected cells and interfered with the NS1 activities leading to replication inhibition of viruses belonging to different subtypes and types including avian H5N1, swine H1N1 and H3N2, human H1N1 and H3N2 and influenza B virus (Yodsheewan et al. 2013; PMID: 23928258).
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Artikelnummer ABAAb03635-10.3
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab03635-10.3
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Various species
Klonalität Recombinant
Methode Western Blotting, ELISA, Inhibition
Isotyp IgG1 kappa
Wirt Human
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