Anti-P-Cadherin (6A9)

Anti-P-Cadherin [6A9], Recombinant, IgG1 kappa, Human

CloneID: 6A9

Antigen Long Description: The original antibody was generated by immunizing mice against a 72-kilodalton (kDa) P-cadherin fragment from A-431 cells.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P22223

Specificity Statement: The antibody is specific for P-Cadherin-1 (CDH3). P-Cadherin-1 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.

Application Notes (Clone): The antibody detected human P-Cadherin from A431 cell lysate by Western blot analysis. The antibody was used to immunoprecipitate P-Cadherin. Further, the antibody was shown to have inhibitory activity, by disrupting P-cadherin-mediated cell-cell adhesion with A-431 cells (Lewis et al., 1994; PMID: 8006450). The antibody detected P-cadherin by immunofluorescence (Owens et al., 2000; PMID: 10708559).

• Artikelnummer: ABAAb02535-10.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab02535-10.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG1 kappa
• Wirt: Human