CloneID: C-11
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by immunizing a BALB/c mouse with keratin-enriched preparations from cultured A431 cells.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for cytokeratin.
Application Notes (Clone): The original version of this antibody was used for immunocytochemistry on endometrial tissue from whole uteri of regularly cycling women (Ciocca et al., 1983; PMID: 6348061). This antibody was also used for immunohistochemistry on CIS from a DMBA-treated rat (Heffelfinger et al., 2003; PMID: 12861040), on histological sections of CIS from untreated and 6-week ZD6474 cohorts (Heffelfinger et al., 2004; PMID: 15170218), on mouse thymus (Song et al., 2008; PMID: 18824586), and on fresh samples from either tumors or normal tissues distant from tumors (Bártek et al., 1991; PMID: 1716305). This antibody was also used for immunofluorescence on Skin pieces of juvenile goldfish (Mauger et al., 2009; PMID: 19068235). This antibody was used in a western blot on mouse intestine lysates (Rhee et al., 2009; PMID: 19188353), on K562 and MDAMB231 cell lines (Kershaw et al., 2015; PMID: 25957999), and on filament-enriched preparations using this antibody (Bártek et al., 1991; PMID: 1716305).
Deutsch
English
