Anti-paraoxon (organophosphate) (A.17 L47K)

Anti-paraoxon (organophosphate) [A.17 L47K], Recombinant, IgG kappa, Rabbit

CloneID: A.17 L47K

Antigen Long Description: The original antibody was generated via phage display from the Griffin.1 library by panning against reactive phosphonate ester 1.

Origin Pub PMID: 32859757

Buffer Composition: PBS only.

Specificity Statement: This antibody is specific for paraoxon.

Application Notes (Clone): This antibody is a covalent trap for Paraoxon and other organophosphate substrates, catalyzing the hydrolysis reaction through the S_N2 mechanism. The catalytic parameters of this antibody were measured, and its K_D was found to be 170 ± 8 μM; it exhibited a 340-fold reactivity enhancement for paraoxon relative to wild-type Ig-paraoxonase. Furthermore, its crystal structure in complex with paraoxon was determined (Mokrushina et al., 2020; PMID: 32859757).

• Artikelnummer: ABAAb04213-23.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04213-23.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Recombinant
• Isotyp: IgG kappa
• Wirt: Rabbit