Anti-Paxillin (LD4 Motif) (LD4 sAB)

Anti-Paxillin (LD4 Motif) [LD4 sAB], Recombinant, IgG kappa, Rabbit
Artikelnummer
ABAAb00396-23.0-BT
Verpackungseinheit
1 mg
Hersteller
Absolute Antibody

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CloneID: LD4 sAB

Antigen Long Description: Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P49023

Specificity Statement: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

Application Notes (Clone): This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.
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Artikelnummer ABAAb00396-23.0-BT
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab00396-23.0-BT
Verpackungseinheit 1 mg
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Western Blotting, ELISA
Isotyp IgG kappa
Wirt Rabbit
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