CloneID: MN20B9.34
Antigen Long Description: The original antibody was generated using outer membrane protein preparations from Neisseria meningitidis as immunogen.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q51183; P0DH58
Specificity Statement: This antibody is specific for the P1.4 subtype antigen (HVVVNNKVATH) of serogroup B of Neisseria meningitidis.
Application Notes (Clone): This antibody was used for the identification of PorA subtypes P1.4 using western blot. Antigenicity of the P1.4 epitope of PorA P1.7-2,4 in outer membrane vesicles and liposomes was tested by an inhibition ELISA (PMID: 14741154). This antibody is also reported to be highly bactericidal and was used as a positive control in a serum bactericidal assay (PMID: 14741154).
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