CloneID: 31C6
Heavy Chain modification: Fc Silent™
Antigen Long Description: Recombinant mouse scrapie-Prion protein residues 23-231 (rMoPrP23-231).
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original mouse IgG1 format for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P04156
Specificity Statement: Binds human PrP residues 143-149.
Application Notes (Clone): This is antibody recognises and binds to residues 143-149 of PrP. High Levels of PrP (Prion Protein) are found in the brain of humans and animals that are infected with transmissible spongiform encephalopathies such as Creutzfeld-Jakob disease (CJD), Gerstmann-Straussler disease in humans or bovine spongiform encephalopathy (BSE) in cattle.
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