Anti-PV11 (III20)

Anti-PV11 [III20], Recombinant, IgG lambda, Rabbit

CloneID: III20

Antigen Long Description: The original scFv antibody was selected from a human synthetic scFv phage display library by panning against the PV11 strain of the virus.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.

Specificity Statement: The antibody binds the PV11 strain of the rabies virus.

Application Notes (Clone): The specificity of the scFv-Fc format of the antibody was confirmed by ELISA analysis. The scFv-Fc version of the antibody detected GPRV by western blot analysis. The scFv-Fc version of the antibody bound specifically to the membranes of PV11 infected Vero cells in an immunofluorescence assay. The scFv-Fc version of the antibody neutralized the PV11 strain in a standard in vivo neutralization assay where the virus was incubated with the scFv-Fc fragment before intracranial inoculation in mice (Ray et al., 2001; PMID: 11472431).

• Artikelnummer: ABAAb03527-23.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03527-23.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Virus
• Klonalität: Recombinant
• Methode: Immunofluorescence, Western Blotting, ELISA
• Isotyp: IgG lambda
• Wirt: Rabbit