Anti-Pyrrolate Protein (3C8)

Anti-Pyrrolate Protein [3C8], Recombinant, IgG1 kappa, Mouse

CloneID: 3C8

Antigen Long Description: The original antibody was isolated from the repertoire of the B-1a cell populations in the apoE deficient (apoE−/−) mice. Spleen cells from male apoE−/− mice at 21 weeks of age were fused with P3/U1 murine myeloma cells, and after screening based on specific binding to pyrBSA

Origin Pub PMID: 35031322

Buffer Composition: PBS only.

Specificity Statement: This antibody reacts specifically with pyrrolated protein and does not cross react with DNA. Lysine N-pyrrolation is a post translational modification, a unique covalent modification that converts lysine residues to Nε-pyrrole-L-lysine (pyrK). It imparts electronegative properties to proteins, causing them to mimic DNA and the proteins acquire an electrical conductivity via lysine N-pyrrolation.

Application Notes (Clone): This antibody is recommended for determination of pyrrolated proteins in a sample. The binding reactivity of this antibody towards pyrrolated-BSA protein was determined using ELISA. This antibody does no cross react with DNA in ELISA (PMID: 35031322).

• Artikelnummer: ABAAb03261-1.1-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03261-1.1-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG1 kappa
• Wirt: Mouse