Anti-Quadruplex DNA (5E11)

Anti-Quadruplex DNA [5E11], Recombinant, IgG kappa, Rabbit
Artikelnummer
ABAAb00392-23.0
Verpackungseinheit
200 μg
Hersteller
Absolute Antibody

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CloneID: 5E11

Antigen Long Description: Ver-3 or d(TGGGGG(TTAGGG)2T

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 13.1 nM. Binds to both the Ver-3 and the Oxy-2 type of quadruplex DNA.

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.
Mehr Informationen
Artikelnummer ABAAb00392-23.0
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab00392-23.0
Verpackungseinheit 200 μg
Mengeneinheit STK
Reaktivität Various species
Klonalität Recombinant
Methode ELISA, Immunohistochemistry
Isotyp IgG kappa
Wirt Rabbit
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