Anti-Quadruplex DNA (5E11)

Anti-Quadruplex DNA [5E11], Recombinant, IgG kappa, Rabbit

CloneID: 5E11

Antigen Long Description: Ver-3 or d(TGGGGG(TTAGGG)2T

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: The antibody binds to quadruplex DNA with a Kd of 13.1 nM. Binds to both the Ver-3 and the Oxy-2 type of quadruplex DNA.

Application Notes (Clone): This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.

• Artikelnummer: ABAAb00392-23.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00392-23.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Recombinant
• Methode: ELISA, Immunohistochemistry
• Isotyp: IgG kappa
• Wirt: Rabbit