Anti-RNase A (cAb-RN05)

Anti-RNase A [cAb-RN05], Recombinant, IgG-Fc Fusion, Rabbit

CloneID: cAb-RN05

Antigen Long Description: The original antibody was generated by immunizing a dromedary (Camelus dromedarius) with bovine RNase A. The affinity matured version of this antibody was generated using synthetic combinatorial libraries.

Buffer Composition: PBS only.

Uniprot Accession No.: P61823

Specificity Statement: This antibody binds bovine RNase A. RNase A is an endonuclease enzyme that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. It acts on single-stranded and double-stranded RNA.

Application Notes (Clone): This antibody binds bovine RNase with an affinity in the picomolar range. This affinity matured version of VHH antibody cAb-RN05 binds bovine RNase with an affinity of Kd= 180 pM (PMID: 17888451). 5′–3′ cUMP that binds into the active site of RNase A does not compete with cAb-RN05 for binding to RNase A in an ELISA (PMID: 10196124).

• Artikelnummer: ABAAb03287-23.159-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03287-23.159-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Cow (Bovine)
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG-Fc Fusion
• Wirt: Rabbit