Anti-Snake venom metalloproteinase TM-3 (SVMP-mc18)

Anti-Snake venom metalloproteinase TM-3 [SVMP-mc18], Recombinant, IgG1 kappa, Human

CloneID: SVMP-mc18

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with natural snake venom metalloproteinase TM-3 purified from crude venom of Protobothrops mucrosquamatus.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: O57413

Specificity Statement: This antibody reacts specifically with snake venom metalloproteinase (SVMP) TM-3 present in the venom of Protobothrops mucrosquamatus. SVMP is a potent fibrinogenolytic protease which cleaves mainly the alpha chain of fibrinogen (FGA) and slightly the beta (FGB) and the gamma (FGG) chains. It has hemorrhagic activity.

Application Notes (Clone): This antibody can be used for the detection of SVMP protein of Trimeresurus mucrosquamatus by ELISA. The binding specifcity of the antibody was further confirmed by detection of the protein in a western blot (CN113832132; PMID: 34899734).

• Artikelnummer: ABAAb04528-10.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04528-10.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Recombinant
• Methode: Western Blotting, ELISA
• Isotyp: IgG1 kappa
• Wirt: Human