Product Description: Anti-STEAP2 Antibody (AZD0516 antibody) is a selective six-transmembrane epithelial antigen of prostate 2 (STEAP2) inhibitor. Anti-STEAP2 Antibody inhibits the proliferation, migration and invasion of prostate cancer cells by blocking the STEAP2-mediated ERK/MAPK signaling pathway. Anti-STEAP2 Antibody is promising for research of prostate cancer[1][2].
Applications: Cancer-Kinase/protease
Formula: N/A
References: [1]Jones LA, et al. Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer. Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):179-187./[2]Zanvit P, et al. Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer. J Clin Invest. 2023 Nov 15;133(22):e169655.
Molecular Weight: N/A
Research Area: Cancer
Target: ERK;p38 MAPK
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