CloneID: mAb-112
Heavy Chain modification: Fc Silent™
Antigen Long Description: Human recombinant single chain pro-uPA.
Origin Pub PMID: 19047064
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P00748
Specificity Statement: The antibody binds to pro-uPA with a Kd of 0.8E-9M.
Application Notes (Clone): The antibody binds to and stabilizes pro-uPA, the zymogen form (inactive) of urokinase-type plasminogen activator. Active uPA catalyzes the conversion of plasminogen to the active protease plasmin, a protease that degrades extracellular matrix proteins. T