Anti-VEGFR2 antibody(DM185); Rabbit mAb

Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor; known as kinase insert domain receptor; is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation; survival; migration; tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors; including Rab GTPase; P2Y purine nucleotide receptor; integrin alphaVbeta3; T-cell protein tyrosine phosphatase; etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Description: Anti-VEGFR2 antibody(DM185); Rabbit mAb

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Target: VEGFR2

Uniprot ID: P35968

Usage: Research use only

Clone ID: DM185

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100

• Artikelnummer: DMADME100185-100
• Hersteller: DIMA Biotechnology
• Hersteller Artikelnummer: DME100185-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: ELISA, Flow Cytometry
• Isotyp: Rabbit IgG
• Wirt: Rabbit
• Konjugat: Unconjugated