Product Description: Antibacterial agent 199 (Compound 2) is an activator for caseinolytic protease (ClpP) with a Kd of 0.7 μM. Antibacterial agent 199 exhibits antibacterial efficacy against Gram-positive strains Staphylococcus aureus, Streptococcus pneumoniae and Gram-negative strain Neisseria meningitidis, with MICs of 16, 0.5 and 0.5 μg/mL, respectively[1].
Applications: COVID-19-immunoregulation
Formula: C37H48N6O8
References: [1]Goodreid JD, et al., Total synthesis and antibacterial testing of the A54556 cyclic acyldepsipeptides isolated from Streptomyces hawaiiensis. J Nat Prod. 2014 Oct 24;77(10):2170-81.
CAS Number: 1629166-56-8
Molecular Weight: 704.81
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Bacterial