Anxiolytic/nonsedative agent-1, CAS 355022-97-8

Description: Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.

CAS Number: 355022-97-8

Formula: C18H15N3O4

Molecular Weight: 337,33

References: Taliani S, et al. Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor. J Med Chem. 2009 Jun 25;52(12):3723-34.

• Artikelnummer: TGMT23445-50mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T23445-50mg
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK