Product Description: AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic[1].
Applications: Cancer-programmed cell death
Formula: C31H44ClFN8O3
Citations: Cancers (Basel). 2020 Jan 29;12(2):311./Gastroenterology. 2024 Jan 24:S0016-5085(24)00064-7./Biomed Pharmacother. 2024 Jun 18:177:116970./bioRxiv. 2024 October 25./Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8./Cell Discov. 2020 Aug 18;6:56./Research Square Print. November 14th, 2022/SSRN. 2023 Feb 10./Theranostics. 2019 Aug 12;9(20):5769-5783.
References: [1]Da-Woon Jung, et al. A Unique Small Molecule Inhibitor of Enolase Clarifies Its Role in Fundamental Biological Processes.ACS Chem. Biol., 2013, 8 (6), pp 1271–1282
CAS Number: 2070014-95-6
Molecular Weight: 631.18
Compound Purity: 99.24
Research Area: Cancer; Metabolic Disease
Solubility: DMSO : ≥ 53 mg/mL/H2O : 12.5 mg/mL (ultrasonic)
Target: Apoptosis;Enolase
Deutsch
English
