(+)-Aphidicolin, CAS 38966-21-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol

Purity: ≥98%

Formula Markup: C20H34O4

Formula Weight: 338.5

CAS Number: 38966-21-1

Notes: (+)-Aphidicolin is a natural tetracyclic diterpene first isolated from the fungus C. aphidicola and shown to have antiviral activity against herpes simplex.{22496} In eukaryotic cells, it is a cell-permeable, reversible inhibitor of DNA replication, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.{22501,22499,22497} Aphidicolin can be used, at 3 μM, to arrest cells in G1/S phase or to increase gene amplification frequency.{22498,22502}

• Artikelnummer: CAY14007-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14007-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK