Description: The ADP-ribosylation factor (ARF) family comprises a group of structurally and functionally conserved proteins, which are members of the Ras superfamily of regulatory GTP-binding proteins. The ARF family is divided functionally into the ARF and the ARF-like proteins. ARF's share more than 60% sequence identity, appear to be ubiquitous in eukaryotes, and are highly conserved evolutionarily. ARF is involved in intracellular protein traffic to and within the Golgi complex. ARF has a number of disparate activities including maintenance of organelle integrity, assembly of coat proteins, as a co-factor for cholera toxin and as an activator of phospholipase D. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)
Conjugate: CF740
Concentration: 0.1 mg/mL
Storage buffer: PBS, 0.1% rBSA, 0.05% azide
Clone: 3F1
Immunogen: Synthetic peptide SNQLRNQ, corresponding to C terminal amino acids 174-180 of Human ARF1.
Antibody Reactivity: ADP-Ribosylation Factor 1/ARF1
References: Note: References for this clone sold by other suppliers may be listed for expected applications.
- J Biol Chem (2009) 284(20): 13948-13957. (WB)
- J Biochem (2016) 159(2): 201-208. (IF; WB)
Entrez Gene ID: 375
Expected AB Applications: IF (published for clone)/WB (published for clone)
Z-Antibody Applications: IF (published)/WB (published)
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