ART812, CAS 2607138-82-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (2S,3S,4S)-N-(3-chloro-4-fluorophenyl)-3,4-dihydroxy-N-methyl-1-[6-methyl-4-(trifluoromethyl)-2-pyridinyl]-5-oxo-2-pyrrolidinecarboxamide

Purity: ≥98%

Formula Markup: C19H16ClF4N3O4

Formula Weight: 461.797613

CAS Number: 2607138-82-7

Notes: A DNA polymerase θ inhibitor (IC50 = 7.6 nM); inhibits MMEJ in a reporter assay using HEK293 cells (EC50 = 240 nM); increases blood levels of micronucleated reticulocytes in mice at 150 mg/kg twice per day; inhibits tumor development in a Brca1- and Shld2-knockout MDA-MB-436 breast cancer rat xenograft model of tumor initiation at 100 mg/kg per day

• Artikelnummer: CAY42904-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42904-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK