Product Description: Asenapine maleate is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with Ki values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic.
Applications: Neuroscience-Neuromodulation
Formula: C21H20ClNO5
References: [1]Stoner SC, et al. Asenapine: a clinical review of a second-generation antipsychotic. Clin Ther. 2012 May;34(5):1023-40./[2]Shahid M, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23(1):65-73./[3]Ohyama M,et al. Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model. Acta Neuropsychiatr. 2016 Dec;28(6):327-336./[4]Ene HM, et al. Effects of repeated asenapine in a battery of tests for anxiety-like behaviours in mice. Acta Neuropsychiatr. 2016 Apr;28(2):85-91.
CAS Number: 85650-56-2
Molecular Weight: 401.84
Compound Purity: 99.95
Research Area: Neurological Disease
Solubility: DMSO : 25 mg/mL (ultrasonic)/H2O : 6.25 mg/mL (ultrasonic;warming)
Target: 5-HT Receptor
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