AT-406, CAS 1071992-99-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (5S,8S,10aR)-N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-pyrrolo[1,2-a][1,5]diazocine-8-carboxamide

Purity: ≥95%

Formula Markup: C32H43N5O4

Formula Weight: 561.7

CAS Number: 1071992-99-8

Notes: AT-406 is an orally bioavailable Smac/DIABLO mimetic and antagonist of the inhibitor of apoptosis proteins (IAPs). It binds to XIAP, cIAP1, and cIAP2 proteins with Ki values of 66.4, 1.9, and 5.1 nM, respectively.{31969} It has been shown to inhibit cancer cell growth in various human cancer cell lines and to induce apoptosis in xenograft tumors in mice.{31969,31968}

• Artikelnummer: CAY19929-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19929-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK