Atorvastatin-d5 (calcium salt), CAS 222412-82-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-(4-fluorophenyl)-ßR,dR-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, hemicalcium salt

Purity: ≥99% deuterated forms (d1 -d3)

Formula Markup: C33H29D5FN2O5 / 1/2Ca

Formula Weight: 562.662243

CAS Number: 222412-82-0

Notes: Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin (Item No. 10493) by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.{37553} Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.

• Artikelnummer: CAY25043-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25043-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung