Avacopan, CAS 1346623-17-3

Product Description: Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM.

Applications: COVID-19-immunoregulation

Formula: C33H35F4N3O2

References: [1]Bekker P, et al. Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study. PLoS One. 2016 Oct 21;11(10):e0164646./[2]Xiao H, et al. C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol. 2014 Feb;25(2):225-31.

CAS Number: 1346623-17-3

Molecular Weight: 581.64

Compound Purity: 99.75

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Complement System

• Artikelnummer: MEXHY-17627-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17627-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK