AZ 13705339, CAS 2016806-57-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-[[[2-[[3-(ethylsulfonyl)-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-fluoro-4-pyrimidinyl][5-(hydroxymethyl)-2-methylphenyl]amino]methyl]-benzonitrile

Purity: ≥98%

Formula Markup: C33H36FN7O3S

Formula Weight: 629.8

CAS Number: 2016806-57-6

Notes: A PAK1 inhibitor (IC50 = 0.33 nM); selective for PAK1 over a panel of 117 kinases at 100 nM; binds to PAK1 and PAK2 (Kd = 0.28 and 0.32 nM, respectively); inhibits S. enterica infection in HAP1 cells at 10 µM; inhibits cell death induced by an antibody targeting Siglec-8 in IL-5-stimulated primary human eosinophils (IC50 = 59 nM)

• Artikelnummer: CAY42087-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42087-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK