Product Description: AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively.
Applications: Cancer-Kinase/protease
Formula: C27H25N5O2
References: [1]Khazak V, et al. Selective Raf inhibition in cancer therapy. Expert Opin Ther Targets. 2007 Dec;11(12):1587-609./[2]Lau KS, et al. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One. 2012;7(7):e41343.
CAS Number: 878739-06-1
Molecular Weight: 451.52
Compound Purity: 99.85
Research Area: Cancer
Solubility: DMSO : ≥ 50 mg/mL
Target: Apoptosis;Raf