Product Description: AZD-7762 is a potent ATP-competitive checkpoint kinase (Chk) inhibitor in with an IC50 of 5 nM for Chk1.
Applications: Cancer-Kinase/protease
Formula: C17H19FN4O2S
References: [1]Zabludoff SD, et al. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Mol Cancer Ther. 2008 Sep;7(9):2955-66./[2]Quin J, et al. Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling. Oncotarget. 2016 Aug 2;7(31):49800-49818.
CAS Number: 860352-01-8
Molecular Weight: 362.4217632
Compound Purity: 99.95
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Checkpoint Kinase (Chk)