AZD-8529 (mesylate), CAS 1314217-69-0

Product Description: AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes[1].

Applications: Neuroscience-Neuromodulation

Formula: C25H28F3N5O6S

References: [1]Justinova Z, et al. The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys. Biol Psychiatry. 2015 Oct 1;78(7):452-62.

CAS Number: 1314217-69-0

Molecular Weight: 583.58

Compound Purity: 99.63

Research Area: Neurological Disease

Solubility: DMSO : 41.67 mg/mL (ultrasonic)

Target: mGluR

• Artikelnummer: MEXHY-107457A-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-107457A-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK