Clone Name: 6J26
Application Note: WB: 1:500 - 1:1000. IHC: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
Uniprot ID: P56817
Antigen Species: Human
Immunogen: The immunogen corresponding to a region within amino acids 22 - 460 of human BACE-1 (Uniport: P56817)
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: beta-secretase 1
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