Product Description: BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
Applications: COVID-19-immunoregulation
Formula: C15H14N2O5S3
References: [1]Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement.J Immunol. 2000 Jan 1;164(1):463-8./[2]Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement. J Immunol. 2000 Jan 1;164(1):463-8.
CAS Number: 217099-44-0
Molecular Weight: 398.48
Compound Purity: 99.87
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 33.33 mg/mL
Target: Complement System