Target: BDNF
Conjugate: HRP
Product Type: Polyclonal
Immunogen: Synthetic peptide from the N-terminal of human BDNF
Swiss-Prot: P23560
Purification: Peptide Affinity Purified
Storage Buffer: 73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide and 0.23mM Citrate in dH2O
Concentration: 1 mg/ml
Specificity: Predicted molecular weight at ~27.9kDa.
Cellular Localization: Secreted
Scientific Background: Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical Nerve Growth Factor. Neurotrophic factors are found in the brain and the periphery. The effects of BDNF on motor neurons might be useful in treating patients with motor neuropathies and ALS (1-3).
References: 1. Wetmore C., Ernfors P., Persson H., Olson L. (1990) Exp. Neurol. 109(2): 141-152.2. Thoenen H., Zafra F., Hengerer B., Lindholm D. (1991) Ann NY Acad Sci. 640: 86-90.3. Chun H.S., Son J.J., Son J.H. (2000) Neuroreport. 11(3): 511-514.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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