Benztropine (mesylate), CAS 132-17-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane, monomethanesulfonate

Purity: ≥98%

Formula Markup: C21H25NO / CH3SO3H

Formula Weight: 403.5

CAS Number: 132-17-2

Notes: Benztropine is an antagonist of M1 muscarinic acetylcholine receptors (Ki = 0.59 nM in rat brain membranes).{26585} It is selective for M1 receptors over the serotonin transporter (Ki = 5,150 nM), however, it also binds to the dopamine transporter and inhibits dopamine reuptake (Kis = 237 and 130 nM, respectively).{26585,20213,26584} Benztropine also inhibits acid sphingomyelinase by 87% when used at a concentration of 10 mM.{26583} Formulations containing benztropine have been used in the management of Parkinson's disease symptoms such as involuntary tremor and dystonia.

• Artikelnummer: CAY16214-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16214-10
• Verpackungseinheit: 10 g
• Mengeneinheit: STK