Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 3ß-hydroxy-lup-20(29)-en-28-al
Purity: ≥98%
Formula Markup: C30H48O2
Formula Weight: 440.70092
CAS Number: 13159-28-9
Notes: Betulinic aldehyde is a triterpenoid that has been found in Z. cambodiana and has diverse biological activities.{48464,48465,48466,48467} It is active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively).{48464,48465} Betulinic aldehyde inhibits dengue virus non-structural protein 5 (NS5) RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% when used at concentrations of 5 and 10 μg/ml, respectively.{48466} It also inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively).{48467}
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