BI-749327, CAS 2361241-23-6

Product Description: BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7[1].

Applications: COVID-19-immunoregulation

Formula: C23H21F3N4O2

References: [1]Lin B L, et al. In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161.

CAS Number: 2361241-23-6

Molecular Weight: 442.43

Compound Purity: 99.91

Research Area: Cardiovascular Disease

Solubility: DMSO : 31.25 mg/mL (ultrasonic)

Target: TRP Channel

• Artikelnummer: MEXHY-111925-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111925-10.1
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK