Product Description: BI-9787 is a zwitterionic inhibitior for ketohexokinase, with an IC50 of 12 and 12.8 nM for hKHK-A and hKHK-C. BI-9787 exhibits good metabolic stability in rat hepatocyte and good pharmacokinetic characteristics in rats[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C24H29F2N5O2S
References: [1]Heine N, et al., Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability. Bioorg Med Chem Lett. 2024 Aug 22;112:129930.
CAS Number: 3043939-18-7
Molecular Weight: 489.58
Compound Purity: 97.82
Research Area: Metabolic Disease
Target: Ketohexokinase