BI-99179, CAS 1291779-76-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-(2-benzoxazolyl)phenyl]-N-methyl-3S-[(1R-oxopropyl)amino]-cyclopentanecarboxamide

Purity: ≥98%

Formula Markup: C23H25N3O3

Formula Weight: 391.5

CAS Number: 1291779-76-4

Notes: BI-99179 is an inhibitor of fatty acid synthase type I (FAS-I; IC50 = 79 nM), a multifunctional enzyme that catalyzes the conversion of acetyl-coenzyme A (acetyl-CoA; Item No. 16160) and malonyl-CoA (Item No. 16455) to long-chain fatty acids.{51830} It is selective for FAS-I over 30 other enzymes, receptors, and ion channels at 10 µM. BI-99179 inhibits the incorporation of 14C-acetate in mouse N-42 hypothalamus cells (IC50 = 570 nM). It reduces the proliferation of GaMG human glioma cells when used at a concentration of 10 µM.{51831}

• Artikelnummer: CAY41307-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41307-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK