Product Description: Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. Bimatoprost is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. Topical application of bimatoprost induces fat atrophy and causes a deepening of the eyelid sulcus[1][2][3][4][5][6].
Formula: C25H37NO4
References: [4]Patil A J, et al. Bimatoprost–a review[J]. Expert opinion on pharmacotherapy, 2009, 10(16): 2759-2768./[5]Woodward, et al. "Bimatoprost: a novel antiglaucoma agent." Cardiovascular drug reviews 22.2 (2004): 103-120./[6]Crowston, et al. "Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice." Investigative ophthalmology & visual science 46.12 (2005): 4571-4577./[1]Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7./[2]Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7./[3]Stamer W D, et al. Proposed mechanism of long-term intraocular pressure lowering with the bimatoprost implant[J]. Investigative Ophthalmology & Visual Science, 2023, 64(3): 15-15.
CAS Number: 155206-00-1
Molecular Weight: 415.57
Compound Purity: 99.83
Research Area: Endocrinology; Cardiovascular Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: MMP;Prostaglandin Receptor
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