Product Description: Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
Applications: Neuroscience-Neurodegeneration
Formula: C21H20F7N3O4S
References: [1]Alberati D, et al. Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia. Neuropharmacology. 2012 Feb;62(2):1152-61./[2]Pinard E, et al. Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia. J Me
CAS Number: 845614-11-1
Molecular Weight: 543.46
Compound Purity: 99.59
Research Area: Neurological Disease
Solubility: DMSO : ≥ 50 mg/mL
Target: GlyT
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