BMS 182874 (hydrochloride), CAS 1215703-04-0

BMS 182874 (hydrochloride), CAS 1215703-04-0
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MEXHY-103458-0
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Product Description: BMS 182874 hydrochloride is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 hydrochloride reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].

Formula: C17H20ClN3O3S

References: [1]Abdullaha M, et.al. Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship. ACS Omega. 2023 May 9;8(20):17591-17608.

CAS Number: 1215703-04-0

Molecular Weight: 381.88

Research Area: Metabolic Disease; Cardiovascular Disease

Target: Endothelin Receptor
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Artikelnummer MEXHY-103458-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-103458-0
Verpackungseinheit Get quote
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