Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-[[5-methoxy-6-(phenylmethoxy)-1H-indol-2-yl]carbonyl]-1-(phenylmethyl)-L-histidine, methyl ester
Purity: ≥98%
Formula Markup: C31H30N4O5
Formula Weight: 538.6
CAS Number: 1598424-76-0
Notes: An Asc-1 inhibitor; selectively inhibits Asc-1 in HEK293 cells expressing Asc-1 (IC50 = 36.8 nM) over 40 other transporters (IC50s = >10 µM); inhibits serine, cysteine, glycine, and alanine import and cAMP-induced increases in the OCR and decreases UCP1 levels in primary human white and brown adipose cells at 100 nM; decreases the number of malformed neurons and reduces contextual fear memory deficits in a mouse model of surgery-induced brain damage when intracerebroventricularly infused