Product Description: BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC50s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation[1][2].
Applications: COVID-19-immunoregulation
Formula: C25H40N8O2
References: [1]Norman P. et al. A dual CCR2/CCR5 chemokine antagonist, BMS-813160? Evaluation of WO2011046916. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24./[2]Cherney RJ, et al. BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate. ACS Med Chem Lett. 2021 Oct 15;12(11):1753-1758.
CAS Number: 1286279-29-5
Molecular Weight: 484.64
Compound Purity: 99.93
Research Area: Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease