BRD2492, CAS 1821669-43-5

Product Description: BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01 μM and 11.13 μM for T-47D and MCF-7 cells, respectively[1].

Applications: Cancer-programmed cell death

Formula: C20H18N4O2

References: [1]Linda Schäker-Hübner, et al. Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors. ChemMedChem. 2022 May 4;17(9):e202100755.

CAS Number: 1821669-43-5

Molecular Weight: 346.38

Compound Purity: 99.18

Research Area: Cancer

Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HDAC

• Artikelnummer: MEXHY-124053-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-124053-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK