BRD73954, CAS 1440209-96-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide

Purity: ≥95%

Formula Markup: C16H16N2O3

Formula Weight: 284.3

CAS Number: 1440209-96-0

Notes: BRD73954 is a dual inhibitor of histone deacetylase 6 (HDAC6) and HDAC8 (IC50s = 36 and 120 nM, respectively).{27579} It is selective for HDAC6 and -8 over HDAC1-5, -7, and -9 (IC50s = 12, 9, 23, >33, >33, 13, and >33 µM, respectively). BRD73954 (10 µM) increases acetylation of α-tubulin, a known HDAC6 substrate, but not histone H3, a substrate for HDAC1, -2, and -3, in HeLa cells.

• Artikelnummer: CAY16919-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16919-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK