BRD9539, CAS 1374601-41-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid

Purity: ≥98%

Formula Markup: C24H21N3O3

Formula Weight: 399.4

CAS Number: 1374601-41-8

Notes: BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 µM.{20922} It inhibits polycomb repressive complex 2 (PRC2) to a similar extent with 54 and 43% activity remaining for G9a and PRC2, respectively, when used at a concentration of 10 µM. It is selective for G9a and PRC2 over SU39H1 and NDMT1 up to a concentration of 40 µM. It is more potent than BRD4770 (Item No. 11787) in enzyme assays but has no activity in cell-based assays when used at concentrations of 5 and 10 µM.

• Artikelnummer: CAY11788-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11788-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK