Bulk Anti-Human CD1d (D5) Antibody - Ultra-Low Endotoxin

Bulk Anti-Human CD1d (D5) Antibody - Ultra-Low Endotoxin, Host: Mouse, Mouse IgG2b
Artikelnummer
ICH1177UL-5MG
Verpackungseinheit
5mg
Hersteller
Ichorbio

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Target: CD1d

Clone: D5

Specificity: Clone D5 recognizes an epitope on human CD1d

Purification method: This monoclonal antibody was purified using Protein A

Antigen Distribution: CD1d is expressed on monocytes, DCs, macrophages, and epithelial cells

Background: CD1d antibody, D5, recognizes human CD1d, also known as CD1.1 and Ly-38, a 48 kDa type 1 membrane glycoprotein that belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. CD1d is expressed on epithelial cells and monocyte-derived antigen presenting cells (APCs), including monocytes, DCs, and macrophages. CD1d is an MHC class I-like molecule involved in the presentation of lipid antigens, such as α-galactosylceramide (α-GalCer), to a highly conserved T cell subset, named invariant natural killer T (iNKT) cells or CD1d-restricted T cells1. Following activation, iNKT cells rapidly proliferate and produce large amounts of cytokines and cytolytic mediators

Immunogen: CD1d a1-a2 domains

Concentration: ≥ 5.0 mg/ml

Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.

Purity: >98% by SDS-PAGE and HPLC

Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method

Aggregation: Aggregation level ≤ 1%

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1177UL-5MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1177UL-5MG
Verpackungseinheit 5mg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunoprecipitation, Western Blotting
Isotyp Mouse IgG2b
Wirt Mouse
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